The Mechanisms of Organophosphorus Pesticides-induced Hyperglycemia:a Review of Recent Researches
- VernacularTitle:有机磷农药毒性引发高血糖机制的研究进展
- Author:
Li XIANG
;
Jianshe TANG
- Publication Type:Journal Article
- Keywords:
Organophosphorus;
Hyperglycemia;
Mechanisms
- From:
Journal of Environment and Health
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
As one of important sorts of pesticides,organophosphorus pesticides(OPPs) are used widely in the world.They can cause serious environmental problems and have some adverse effects on the health of people and animals.They can induce acute neurotoxicity and delayed neurotoxicity,and result in the damages of organs.The objective of this paper is to provide a brief review of the mechanisms involved in the OPPs-induced hyperglycemia.OPPs can influence body glucose homeostasis by several mechanisms including oxidative stress,nitrosative stress,inhibition of cholinesterase,inhibition of paraoxonase,disturbance in metabolism of liver tryptophan and so on.