Advances on DNA methylation for noninvasive tumor molecular diagnosis
- VernacularTitle:DNA甲基化在肿瘤无创性分子诊断中的研究进展
- Author:
Zhaohui HUANG
;
Xiang DU
- Publication Type:Journal Article
- Keywords:
DNA methylation;
epigenetics;
circulating DNA;
diagnosis;
stool;
urine
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
DNA methylation is one of the most common epigenetic events in eukaryotic cell.Aberrant DNA methylation is tightly related to tumorigenesis.Recent evidence indicates that DNA methylation is a promosing biomarker for cancer.The cancer-associated DNA methylation events could be detected from serum(plasma),urine,stool and bronchoalveolar lavage,providing a new choice for noninvasive cancer diagnosis.In this review,we summarized the advances on DNA methylation for noninvasive cancer diagnosis.
