Relationship of gene polymorphisms of fatty acid binding protein-2 and apolipoprotein E with coronary heart disease in type-2 diabetic patients
- VernacularTitle:脂肪酸结合蛋白、载脂蛋白E基因多态性与2型糖尿病并发冠心病的关系
- Author:
Yurong SHI
;
Haiyan ZHOU
;
Yao ZHANG
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
coronary heart disease;
fatty acid binding protein-2;
gene polymorphism;
apolipoprotein-E
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship of fatty acid binding protein-2(FABP2)and apolipoprotein E(ApoE)with coronary heart disease(CHD)in type-2 diabetes mellitus(T2DM)patients.Methods FABP2 and ApoE gene polymorphisms were detected by PCR-RFLP.At the same time all CHD in T2DM patients' serum triglyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol were(HDLC),low-density lipoprotein cholesterol(LDLC)were detected.Results The T-allele frequencies of FABP2 were higher(P
