Expressions of ?-catenin and ?-catenin in human non-small cell lung cancer and their clinical significance
- VernacularTitle:?-连环素和?-连环素在非小细胞肺癌中的表达及其临床意义
- Author:
Xiaomin DANG
;
Zhongmin SUN
;
Dong SHANG
- Publication Type:Journal Article
- Keywords:
lung neoplasm;
?-catenin;
?-catenin;
immunohistochemistry
- From:Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expressions of ?-catenin(?-cat)and ?-catenin(?-cat)and their relation with development and prognosis of non-small cell lung cancer(NSCLC).Methods Expressions of ?-cat and ?-cat were immunohistochemically studied in 43 specimens of NSCLC and 7 cases of normal lung tissues.Results Of the 43 NSCLC cases,the abnormal rate of ?-cat and ?-cat expression was 72.1% and 65.1%,respectively.Differentiation and lymph node involvement had a significantly positive correlation with abnormal expression of ?-cat or ?-cat(P
