Value of Chemosensitivity Assay In Vitro on Breast Cancer
- VernacularTitle:乳腺癌体外药敏实验结果分析及价值
- Author:
Zhengyou HUANG
;
Zhiwen LI
;
Yunrong QIN
- Publication Type:Journal Article
- Keywords:
Drug sensitivity experiment of tumor;
Beast cancer;
Tissue culture-end point staining-computer image analysis;
Individual chemotherapy
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of chemosensitivity assay in vitro on breast cancer.MethodsIn vitro chemosensitivity of 6 species of chemotherapeutic agents applied to 38 cases of breast cancer patients were detected by tissue culture-end point staining-computer image analysis(TECIA).ResultsThe sensitivity to chemotherapeutic agents commonly used in the breast cancer level from high to low was as follow:Doxorubicin(ADM),Paclitaxel(TAX),Vinorelbine(NVB),Cyclophosphamide(CTX),Cisplatin(DDP)and Fluorouracil(FU).ConclusionDrugs sensitivity experiment of cancer in vitro by TECIA has an important value to instruct clinical medication and individual chemotherapy for breast cancer.
