The expression of CD1a and E-cadherin in condyloma accuminatum tissues and the ultramicrostructure of Langerhans cell
- VernacularTitle:尖锐湿疣组织CD1a、上皮细胞钙粘素分子及其mRNA的表达和朗格汉斯细胞的电镜观察
- Author:
Yongzheng PAN
;
Fei WANG
;
Dan LUO
- Publication Type:Journal Article
- Keywords:
Condyloma accuminatum;
Langerhans cell;
CD1a;
E-cadherin;
Ultramicrostructure
- From:
Chinese Journal of Immunology
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the changes in number,morphology and function of Langerhans cells and the molecular mechanisms in the tissues of condyloma accuminatum.Methods:CD1a,E-cadherin were measured by streptavidin peroxidase method and reverse transcriptase PCR in 26 CA lesions and 10 normal controls.Ultramicrostructure of LC was observed by transmission electronic microscope(TEM).Results:In CA tissues,the number of CD1a+ LC decreased(10.66?11.71,P