Role of Stereotactic Surgery for Treatment of Spontaneous Intracerebral Hematomas.
- Author:
Seong II HA
1
;
Jong Soo LEE
;
Seung Jae LEE
;
Hyo Il PARK
Author Information
1. Department of Neurosugery, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Spontaneous intracerebral hematoma;
Stereotactic evacuation;
Urokinase
- MeSH:
Anesthesia, Local;
Consciousness;
Craniotomy;
Diagnosis;
Follow-Up Studies;
Ganglion Cysts;
Hematoma*;
Hemorrhage;
Humans;
Pons;
Urokinase-Type Plasminogen Activator
- From:Journal of Korean Neurosurgical Society
1996;25(2):297-302
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Computerized tomography(CT) have been available for diagnosis and localization of intracerebral hematoma. CT-guided stereotactic evacuation of spontaneous intracerebral hematoma was performed in 34 cases; 25 basal ganglionic hematomas with or without ventricular perforation, 4 subcortical, 3 thalamic, 1 cerebellar and 1 pontine. The biplane CT image were taken to determine the coordinates of the target point, which was the center of the hematoma. The liquefied or solid portion of the hematoma was aspirated through a burr-hole under local anesthesia. And a silastic tube(3.3mm in outer diameter and 2.0mm in inner diameter) was then inserted into the center of the hematoma. Immediately after the first trial of hematoma aspiration, urokinase(6000IU/5ml saline) was administered through the tube. Subsequently, aspiration and infusion of urokinase were repeated every 6 or 12 hours until the hematoma was almost completely evacuated. The follow-up results indicate that this procedure was more superior over the conventional craniotomy. This CT-guided stereotactic operation has the following advantages; 1) the procedure is simple and safe; 2) the procedure can be performed under local anesthesia; and 3) the hematoma can be completely drained with the aid of urokinase. This procedure can be used as a standard treatment for intracerebral hematoma. We have draw the following conclusions; As a result of the above study 1) Stereotactic surgery is more effective in the patients with neurologic grade 3 than conservative one (p<0.05). 2) To use urokinase or perform the early surgery within 24 hours did not seem to be the cause of rebleeding. 3) In the case of pons or cerebellar hemorrhage, stereotactic surgery had definite benefit in the recovery of consciousness even if recovery of motor function was dismal. 4) In patients with spontaneuous ICH, the favorable prognostic indicatiors were as follows: the size of hematoma less thas 50ml, no signs of transtentorial herniation and patient's age under 60.