Research advancement of pancreatic cancer stem cells
- VernacularTitle:胰腺癌干细胞研究进展
- Author:
Yongqiang HUA
;
Luming LIU
- Publication Type:Journal Article
- Keywords:
carcinoma;
pancreatic carcinoma;
cancer stem cell
- From:
China Oncology
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The stem cell hypothesis for cancer suggests that only a specific subset of cancer cells within each tumor is responsible for tumor initiation and propagation,termed cancer stem cells(CSCs),which have a character of self-renewal and multilineage differentiation,and responsible for the recurrence,metastasis and resistance to therapy.The CSC of pancreatic cancer were isolated and identified in 2007,and recent data has been reported to confirm the change of the related signal pathway,the relationship with metastasis,therapy resistance and the puzzle.This review article summarizes the latest advances with regard to the pancreatic cancer stem cells.
