Effects of ginsenoside Rg-1 on the expressions of interleukin-6,bone gla protein in periodontal tissues in periodontitis rats
- VernacularTitle:人参皂甙Rg-1对大鼠牙周组织中白介素6、骨钙素水平的影响
- Author:
Qian YANG
;
Zhanhai YU
;
Jiandong DU
;
Guoying ZHANG
;
Fude HE
- Publication Type:Journal Article
- Keywords:
Ginsenoside Rg-1;
Periodontitis model;
Immunohistochemistry;
Interleukin-6;
Bone gla protein
- From:
Journal of Practical Stomatology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine the effects of ginsenoside Rg1 on the expression levels of bone gla protein(BGP) and cytokine interleukin-6(IL-6) in the periodontium of experimental periodontitis rats.Methods:One hundred 160-200 g Wistar rats were randomly divied into ten groups.Group A used as control were killed at the beginning of the experiment.Group B-J were experimental periodontitis models.Group B-E received the therapy of ginsenoside Rg1 were killed at 1st,2nd,3rd and 4th weeks.Group F-J received no treatment as periodontitis control were killed at 0,1st,2nd,3rd and 4th weeks.The expression levels of BGP and IL-6 in the periodontium were measured by immunohistochemistry.Results:The expression levels of BGP in the group F were significantly lower than that in the group A,the expression levels of IL-6 in the group F were much higher than that in the group A(P
