Effects of Qingluotongbi granule on RANKLE expression in T lymphocytes from RA patients
- VernacularTitle:清络通痹颗粒对RA患者外周血T淋巴细胞表达RANKL的影响
- Author:
Xueping ZHOU
;
Lingling ZHOU
;
Min JIA
;
Mingyan WANG
;
Yan LU
- Publication Type:Journal Article
- Keywords:
Qingluotongbi granule(QLT granule);
Rheumatoid arthritis(RA);
RANKL(receptor activator of nuclear factor-?B ligand);
Flow cytometry
- From:
Chinese Journal of Immunology
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of Qingluotongbi granule(QLT) on RANKL(receptor activator of nuclear factor-?B ligand) expression in peripheral blood T lymphocytes of RA patients.Methods:RANKL expression of peripheral blood T lymphocyts was examined using flow cytometry.Six cases of RA patients were enrolled with six healthy volunteers as the control.Meanwhile examination for the level of RANKL expression in T cells after incubation in presense of QLT-contained serum was observed.Results:RANKL expression of peripheral blood T lymphocytes was much higher in active state RA patients than in healthy people(P