Observing on relationship in changes of OPN,IL-18 levels with hepatic function in patients with chronic hepatic disease infected by HBV
- VernacularTitle:乙型肝炎肝硬化患者外周血骨桥蛋白与IL-18水平变化的临床意义
- Author:
Liulan PAN
;
Xiaoqi ZHOU
;
Yuhua ZHOU
;
Yueli TIAN
;
Dongfu LI
- Publication Type:Journal Article
- Keywords:
Hepatitis B,chronic;
Hepatitis B-related cirrhosis;
OPN;
Cytokine/IL-18
- From:
Chinese Journal of Immunology
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe clinical significance between changes of OPN,IL-18 levels and relation ship with hepatic function in patients with chronic hepatic disease infected by HBV.Methods:The levels of OPN,IL-18 in peripheral blood of 102 patients with chronic hepatitis B,34 patients with hepatitis B-related cirrhosis,95 HBV carriers and 20 healthy people as the control group were respectively detected with ELISA.Results:The levels of OPN and IL-18 in chronic hepatitis B and hepatitis B-related cirrhosis groups were significantly increased compared with that of health control group(P
