Effect of ligustrazine on TGF-?1 of patients with bronchial asthma
- VernacularTitle:川芎嗪对支气管哮喘患者外周血TGF-?1水平的影响
- Author:
Xiaomei YUAN
- Publication Type:Journal Article
- Keywords:
bronchial asthma;
transforming growth factor-?1 (TGF-?1);
Ligustrazine
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2003;0(06):-
- CountryChina
- Language:Chinese
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Abstract:
Objective To investigate the change of transforming growth factor-?1 (TGF-?1) in peripheral blood in patients with bronchial asthma and the effect of traditional Chinese medicine Ligustrazine on it. Methods We recruited 80 normal healthy people as the control group and 160 hospitalized patients, including 80 moderate cases and 80 severe cases of bronchial asthma. TGF-?1 in peripheral blood of the patients was detected by enzyme linked immunosorbent assay. The patients were treated with conventional therapy or conventional therapy added Ligustrazine; TGF-?1 in peripheral blood before and after treatment was detected and compared. Results The level of peripheral blood TGF-?1 was higher in the patient group than in the control group obviously (P
