Effect on the micro- and ultramicro-structure of intrahepatic bile duct mediated by hypoxic preconditioning after liver graft
- VernacularTitle:低氧预适应对移植肝内胆管的显微及超微结构的影响
- Author:
Peijian ZHANG
;
Bin ZHOU
;
Cheng JIN
;
Yong LI
;
Tian TIAN
;
Min FENG
;
Xinyan LIU
- Publication Type:Journal Article
- Keywords:
Cell hypoxia?Transplants?Bile duct, intrahepatic?Micro-structure?Ultramicro-structure
- From:
Chinese Journal of Current Advances in General Surgery
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the change of the micro- and ultramicro-structure of in- trahepatic bile duct after liver graft and the protection of hypoxic preconditioning. Methods: The model of orthotopic autologous liver transplantation was used, thirty SD rats were randomly divided into three groups. A: orthotopic autologous liver transplantation group; B: hypoxic preconditioning before operation group; C: sham operation group. The serum bilirubin ,the micro-structure of biliary epithelial cell and the ultramicro-structure of cholangiole were determined in three groups after 48hours after operation. Results: As compared with B group: the serum bilirubin increased (P
