EFFECT OF GRAPE PROCYANIDIN ON PLASMA GMP140 AND TXB_2 IN RATS FED WITH HIGH FAT DIET
- VernacularTitle:葡多酚对高脂膳大鼠血浆?颗粒膜蛋白140和血栓素B_2的影响
- Author:
Huiqin DU
;
Jinyi ZHONG
- Publication Type:Journal Article
- Keywords:
GPC;
GMP140;
TXB2
- From:
Acta Nutrimenta Sinica
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effect of grape procyanidin (GPC) on the levels of plasma?-granule membrance protein 140 (GMP140) and thromboxane B2 (TXB2 ) in rats. Method:Wistar rats fed by high fat diet (HFD) were given GPC i.g. at different doses for 6 w, and the levels of plasma GMP140 and TXB2 were examined by radioimmunoassay (RIA). Result:Plasma GMP140 and TXB2 levels of high dose GPC were respectively 7.89?1.02ng/ml, 131.71?42.13 pg/ml, significantly lower than those of HFD group. Conclusion:GPC could inhibit the increase of plasma GMP140 and TXB2 induced by high fat diet in rats.
