Effect of Cypermethrine on Sex Hormones Level in Serum in Female Rats
- VernacularTitle:氯氰菊酯对雌性大鼠血清性激素的影响
- Author:
Haibin LI
;
Jingzhuan XI
;
Jun LI
- Publication Type:Journal Article
- Keywords:
Cypermethrine;
Sex hormone;
Rats
- From:
Journal of Environment and Health
2007;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To studay the adverse effect of cypermethrine(CP)on sex hormones level in the serum in female rats. Methods Fifty female SD rats(90-110g)were randomly divided into 5 groups,negative control(earthnut oil),3 CP treatment groups(20,40 and 80mg/kg body)and positive control(E_2:100?g/kg body).A 28-day oral test was performed according to the procedure recommended by OECD.Results Compared with the negative group,the level of FSH,LH and P in the serum of rats significantly decreased with the increase of cypermethrine dose(P
