Eosinophil infiltration and peritubular capillary C4d deposition in acute renal allograft rejection
- VernacularTitle:急性排斥移植肾组织嗜酸性粒细胞浸润及C4d沉积
- Author:
Guangchen ZHOU
;
Leishi LI
;
Zhihong LIU
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Acute humoral rejection;
Eosinophil;
C4d
- From:
Chinese Journal of Immunology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the correlation between deposition of C4d along peritubular capillaries (PTC) and interstitial eosinophilic infiltration in renal allografts.Methods:Deposition of C4d in kidneys was assayed by indirect immunoflourescence of the renal allograft biopsies.Twenty-six patients were demonstrated strongly diffuse staining of PTC,who were defined as C4d+ group,while the biopsies of thirty patients with acute rejection exhibited negative for PTC C4d staining served as the controls,who were defined as C4d-group.Eosinophils were counted under microscope.Results:The C4d+group was demonstrated significantly greater interstitial eosinophilic infiltration than did the C4d-group(P
