Prevention of Postoperative Acute Renal Failure in Patients with Malignant Obstructive Jaundice
- VernacularTitle:恶性梗阻性黄疸根治性切除术后急性肾功能衰竭的预防
- Author:
Xiaoqin YANG
;
Yong ZHOU
- Publication Type:Journal Article
- Keywords:
Malignant obstructive jaundice Acute renal failure Perioperative period RIFLE criteria
- From:
Chinese Journal of Bases and Clinics in General Surgery
2008;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protection of renal function and the prevention of acute renal failure (ARF) in patients with malignant obstructive jaundice in perioperative period of radical resection. Methods A series of clinical interventions had been taken since 2004 in our treatment team, including control of endotoxemia, depression of biliary tract before operation, maintenance of adequate effective blood volume, nutritive support, administration of mannitol and low dose of furosemide, and avoidance of disseminated intravascular coagulation. The incidence of perioperative ARF in 206 patients with malignant obstructive jaundice who had been radically resected from 2000 to 2007 was retrospectively studied, and the RIFLE criteria was used for ARF classification. This study was progressed in two periods. The first one was from Jan. 2000 to Dec. 2003, and the second one was from Jan. 2004 to Dec. 2007. Results After 2003, the proportion of radical resection rose from 44.8% to 57.1% (P