Experimental research on angelica amylose to ameliorate swelling of rats toes resulted from adjuvant-induced arthritis (AIA) and writhing response caused by the acetic acid
- VernacularTitle:当归多糖对佐剂性关节炎足趾肿胀值及小鼠醋酸作用扭体反应的实验研究
- Author:
Shenzhi WANG
;
Fuyuan FAN
;
Xuanling HE
- Publication Type:Journal Article
- Keywords:
Angelica amylose;
Rheumatoid arthritis;
Experimental research;
Rat;
Mouse
- From:
Chinese Journal of Immunology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the functional mechanism for therapeutic effects of angelica amylose in mice and rats with adjuvant-induced arthritis (AIA) and its effect of abirritation.Methods:Adjuvant arthritis was induced in either mice or rats.The effect of angelica amylose on rats’ arthritis and on mouse writhing response caused by acetic acid were observed.Tripterygium wilfordii was used as the positive drug for control.Results:Angelica amylose had obvious inhibition on mice writhing response and rats’ adjuvant-induced arthritis.Conclusion:Angelica amylose has effects of abirritation and anti-AIA.