MRI Manifestations of MELAS Syndrome
- VernacularTitle:MELAS综合征的MRI表现
- Author:
Jianjun XIU
;
Chuanfu LI
;
Jinshan ZHANG
;
Qingshi ZENG
;
Tao GU
- Publication Type:Journal Article
- Keywords:
brain;
MELAS syndrome;
mitochondrial encephalomyopathy;
MR imaging
- From:
Journal of Practical Radiology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate MR imaging characteristics of MELAS syndrome.Methods The clinical data and MRI features of 13 cases with MELAS syndrome were retrospectively analyzed.Results Multiple hypointense on T1WI and hyperintense on T2WI lesions were showed predominantly in the gray matter of the temporal, parietal and occipital lobes. The lesions crossed vascular boundaries. No stenosis and occlusion of main artery were displayed by MRA.Basal ganglia calcifications and cerebral atrophy with widening of ventricles were also frequent found. Increased ADC value of the leison on DWI and appearance of Lac peak on1H-MRS were useful in diagnosis.Conclusion There are some characteristics of MRI in patients with MELAS syndrome.Combined clinical informations with neuroimaging and muscle biopsy, the diagnosis of MELAS syndrome can be made correctly.
