Therapeutic effect of Swertia Mussotii Franch on immunological liver injury in mice
- VernacularTitle:藏药川西獐牙菜对小鼠免疫性肝损伤的治疗作用
- Author:
Min XU
- Publication Type:Journal Article
- Keywords:
immunity;
liver injury;
Swertia mussotii Franch;
organ index;
alanine aminotransferase(ALT);
aspartate aminotransferase(AST)
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the therapeutic effect of Swertia mussotii Franch is extracted by alcohol on immunological liver injury in mice,and further evaluate its immun-regulating effect in decreasing aminotransferase and protecting heptocytes. Methods BCG vaccine and lipopolysaccharide were intravenously injected to establish liver injury model.The effects of Swertia mussotii Franch on liver injury were contrasted. Results The high-,medium-and low-dose Swertia mussotii Franch groups which had been administered for 10 consecutive days,had significantly inhibited serum ALT and AST acticities of immunological liver injury;Swertia mussotii Franch could effectively prevent immunological liver injury by BCG+LPS. Conclusion Swertia mussotii Franch can protect mice from immunological liver injury and protect the function of liver.
