Expression of mycoplasma hyorhinis P40 in the tissues of renal cell carcinoma
- VernacularTitle:猪鼻支原体P40蛋白在肾癌组织中的表达及意义
- Author:
Jun CAO
;
Jianping LI
;
Wei CHENG
;
Qi CHEN
- Publication Type:Journal Article
- Keywords:
mycoplasma;
infection;
renal cell carcinoma
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between mycoplasma infection and pathogenesis of renal cell carcinoma(RCC). Methods There were 95 samples of archived embedded tissues of RCC and 60 samples of archived embedded normal renal tissues around the tumor for comparison.We detected mycoplasma hyorhinis P40 expression in archived embedded renal tissues by immunohistochemistry(IHC) with mycoplasma hyorhinis monoclonal antibody(MAb) PD4. Results Mycoplasma hyorhinis P40 was present in 64.2%(61/95 cases) of RCC and in 21.7%(13/60 cases) of the paratumor normal renal tissues in controls.The mycoplasma hyorhinis P40 expression ratio in RCC was significantly higher than that in the normal renal tissue,around the tumor(P
