Effects of tamoxifen on proliferation and ER expression of human hepatocellular carcinoma cells
- VernacularTitle:他莫昔芬对人肝癌细胞增殖及ER表达影响的研究
- Author:
Wenkun BAI
;
Wenqi WANG
;
Changwen SHI
;
Hongwen WU
- Publication Type:Journal Article
- Keywords:
Hepatocellular?Proliferation?Tamoxifen?Receptor,estrogen
- From:
Chinese Journal of Current Advances in General Surgery
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of tamoxifen on proliferation and ER expression of human hepatocellular carcinoma cells.Methods:HepG2 cells were treated with tamoxifen at different concentration and different action time.MTT was used to determine the suppression rate of human hepatocellular carcinoma cell.The effects of tamoxifen on human hepatocellular carcinoma cell ER performance were observed by immunohistochemistry.Results:Tamoxifen inhibited the proliferation of human hepatocellular carcinoma cells and suppressed human hepatocellular carcinoma cell ER performence.Conclusions:Tamoxifen may suppress human hepatocellular carcinoma cell proliferation ER performance.
