Clinical Study on Efficacy of Transcatheter Arterial Chemoembolization Combined with Radiofrequency Ablation in Treating Hepatocellular Carcinoma
- VernacularTitle:双介入法治疗原发性肝癌疗效的临床研究
- Author:
Zhiling QIAN
;
Shichang CUI
;
Haiyan WANG
- Publication Type:Journal Article
- Keywords:
Primary hepatocellular carcinoma Embolization treatment Radiofrequency ablation
- From:
Chinese Journal of Bases and Clinics in General Surgery
2008;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of transcatheter arterial chemoembolization(TACE) combined with radiofrequency ablation(RFA) in treating primary hepatocellular carcinoma(HCC).Methods From March 2004 to March 2006,137 patients with primary HCC underwent TACE alone(n=87) and TACE+RFA(n=50),respectively,after the interventional treatment,all patients periodically received CT reexaminations and alpha fetoprotein(AFP) measurement.The therapeutic efficacy,AFP level and survival rate between two groups were compared with each other.Results In TACE group the effective rate(CR+PR) was 34.5%,AFP decreasing amplitude was 54.2%,and 2 years survival rate was 43.7%.While in TACE+RFA group,the effective rate(CR+PR) was 70.0%,AFP decreasing amplitude was 78.0%,and 2 years survival rate was 62.0%,there were significant differences between two groups(P
