Expression of survivin in brain astrocytoma and analysis of its correlation COX-2
- VernacularTitle:Survivin在脑星形细胞瘤中的表达及其与COX-2相关性研究
- Author:
Shuqing SONG
;
Hongwei WANG
;
Yuming DONG
;
Yunjie WANG
;
Yanqiu FANG
- Publication Type:Journal Article
- Keywords:
Brain astrocytoma;
Survivin;
COX-2;
Immunohistochemistry
- From:
Chinese Journal of Immunology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To approach the actions of survivin and COX-2 during the genesis and development in brain astrocytoma and whether they have dependablity each other.Methods:The expression of survivin and COX-2 was examined by immunohistochemistry SP and their interrelationship was analyzed.Results:The positive expressive rates of survivin in astrocytoma gradeⅠ,Ⅱ,Ⅲ and Ⅳsubgroups were shown in an increased tendency.The expression was weak positive in higher differentiation group,and the positive expressive rate of survivin was increased in the lower differentiation group.There was an significant difference between these two groups(?2=11.20,P
