Expression of destrin in vessel wall tissue of traumatic arterial aneurysm and study of its clinical relativity
- VernacularTitle:细胞骨架蛋白destrin在创伤性动脉瘤血管壁组织中的表达及其临床相关性研究
- Author:
Lei TIAN
;
Lei ZHANG
;
Qingsheng LU
- Publication Type:Journal Article
- Keywords:
traumatic arterial aneurysm;
trauma;
expression;
gene;
protein;
destrin
- From:
Orthopedic Journal of China
2006;0(13):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To investigate the expression of protein destrin in cytoskeleton protein in traumatic arterial aneurysm(TAA) vessel wall tissue and its relationship with clinical representations and pathological characteristics.[Method]Western-blot analysis and RT-PCR were used to detect the quantitative expression of destrin protein in 13 patients with TAA and in the femoral arterial tissues of 8 normal subjects.The difference of protein expression was compared,and the results with clinical data were analyzed statistically.The correlation of unbalanced expression of destrin protein with the clinical presentations was studied.[Result] The expression of destrin in TAA tissue was lower than that in the femoral artery of normal subjects(P
