Research Progress in Animal Models of Parkinson's Disease
- VernacularTitle:帕金森病动物模型的研究进展
- Author:
Jing LIU
;
Yanyong WANG
;
Mingwei WANG
- Publication Type:Journal Article
- Keywords:
Parkinson’s disease;
Animal model;
Neurodegeneration
- From:
Journal of Environment and Health
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson’s disease (PD)is one of familiar neurodegenerative disorder. The pathogenesis of PD,up to now,has not been fully understood. Although heredity,aging and environmental factors were involved,the combination effects of these factors were much concerned. PD animal model is an indispensable tool for exploring the mechanism,neuro-protective drugs and therapy strategies. Some kinds of animal models were introduced in this paper. MPTP mouse model is the most important and most universal use.The consideration of the effect of multiple risk factors may be the start of new era in the research field of PD animal models.