Giant Cell Tumor of Bone:the Correlation between Radiographic Features,Expression of Proliferating Cell Nuclear Antigen and Pathologic Grading
- VernacularTitle:骨巨细胞瘤影像学表现及增殖细胞核抗原表达与病理分级的关系
- Author:
Yi CAI
- Publication Type:Journal Article
- Keywords:
giant cell tumor of bone;
immunohistochemistry;
proliferating cell nuclear antigen;
radiography
- From:
Journal of Practical Radiology
2001;0(06):-
- CountryChina
- Language:Chinese
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Abstract:
Objective To investigate radiological appearances,expression of proliferating cell nuclear antigen(PCNA) of giant cell tumor of bone(GCT) and correlation with its pathologic grading.Methods Expressions of PCNA in 24 GCT specimens were examined using immunohistochemistry technology,radiological appearances were analyzed using score method,correlated with pathologic grading.Results GCTs with low score(0.05).Conclusion Most GCTs can be confirmed by radiography with expression of PCNA added more diagnostic information,which is helpful to preoperative pathologic grading and selection of optimal clinical treatment.
