Perioperative changes of the plasma NO and ET- 1 in the patients with portal hypertension after splenorenal shunt operation
- VernacularTitle:门静脉高压症患者分流术围手术期血浆中NO及内皮素-1水平变化的意义
- Author:
Jun LIU
- Publication Type:Journal Article
- Keywords:
Hypertension, portal;
Nitric oxide;
Endothelins;
Splenorenal shunt, surgical
- From:
Chinese Journal of Current Advances in General Surgery
1999;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective : To study the perioperative changes of the plasma NO and ET- 1 in the patients with the portal hypertension after splenorenal shunt operation. Me thod s: The plasma NO and ET- 1 of the perioperative period was detected in the cirrhotic patients with portal hypertension after distal splenorenal shunt, NO was masuredusing the Griesss and ET- 1 by the radioim- munoassay. R e su lts: Compared with control group and cirhosis group,plasma ET- 1 and NO levels significantly increased in portal hypertension group. Compared with preoperative levels, plasma NO and ET- 1 levels significantly decreased in the patients with portal hypertension after surgery ( P