Effect of Formaldehyde Inhalation on Mice's Learning and Memory
- VernacularTitle:甲醛吸入对小鼠学习记忆能力的影响
- Author:
Xiaoling WANG
;
Fusheng YUAN
;
Zhihong ZHANG
- Publication Type:Journal Article
- Keywords:
Formaldehyde;
Learning;
Memory;
Animal test
- From:
Journal of Environment and Health
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of inhaling formaldehyde on learning and memory in mice. Methods 24 KM mice were randomly divided into four groups: the control group (clean air),the low dose group (1 mg/m3),the moderate dose group (3 mg/m3) and the high dose group (5 mg/m3). The mice were exposed to different concentrations of gaseity formaldehyde,2 h/day,for 14 consecutive days. Then their behavior of learning and memory were tested by step-down test,passive avoidance test and Morris water maze experiment. Results Step-down test showed that the mice in the moderate dose group and the high dose group made notable errors compared with the control group (P
