Role of cell adhesion molecules in bone metastasis of tumor
- VernacularTitle:细胞粘附分子在肿瘤骨转移中的作用
- Author:
Xiaomin NIU
;
Jie ZHANG
;
Shun LU
- Publication Type:Journal Article
- Keywords:
cell adhesion molecules;
tumor cells;
bone metastasis
- From:
China Oncology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Bone metastasis is one of the most common complications of malignant tumors.Cell adhesion molecules(CAMs),including cadherin family,integrin family,selectin family,immunoglobulin superfamily,and hyaladherin,play an important role in bone metastasis of tumor through homotypic and heterotypic adhesive interactions.In this review,molecular and cellular mechanisms underpinning bone metastasis associated with CAMs,the role in a multi-step bone metastatic cascades will be discussed.
