Slit2/Robo1 signaling expression and its correlation with angiogenesis in gastric cancers
- VernacularTitle:Slit2和Robo1蛋白表达与胃癌关系的临床研究
- Author:
Rui JI
;
Xuefeng LU
;
Jindong FU
;
Xusheng JIANG
;
Yan LUO
- Publication Type:Journal Article
- Keywords:
Gastric cancer?Slit?Robo?Microvessel density
- From:
Chinese Journal of Current Advances in General Surgery
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the expressions of Slit2 and its receptor Robo1 in human gastric carcinomas. Methods: The expression of Slit2 protein, Robo1 protein and CD34-labeled microvessel density(MVD) were measured by immunohistochemical staining (SP) in 54 cases of gastric carcinomas and 28 cases of Para-cancer tissues. Results:The positive rates of Slit2 ,Robo1 were 63.0% and 77.8% and the expression of Slit2 , Robo1 and MVD in cancerous tissues were higher than those in para-cancer tissues2(?2=26.586,P