Expressions and Clinicopathologic Significances of CA19-9 and CA125 in Benign and Malignant Lesions of Gallbladder
- VernacularTitle:胆囊良、恶性病变组织中CA19-9和CA125的表达及其临床病理意义
- Author:
Jieqiong LIU
;
Zhulin YANG
;
Xiongyin MIAO
- Publication Type:Journal Article
- Keywords:
Gallbladder adenocarcinoma Chronic cholecystitis Tumor marker
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expressions of CA19-9 and CA125 and their clinicopathologic significances in gallbladder adenocarcinoma, pericancerous tissues and chronic cholecystitis. Methods EnVisionTM immunohistochemistry was used for assaying the expressive levels of CA19-9 and CA125 in the routinely paraffin-embedded sections of specimens from gallbladder adenocarcinoma (n=108), pericancerous tissues (n=46), and chronic cholecystitis (n=35). Results The positive rates of CA19-9 and CA125 were significantly higher in gallbladder adenocarcinoma (49.1%, 51.9%) than those in pericancerous tissues (26.1%, 15.2%) and chronic cholecystitis (14.3%, 5.7%), respectively (P