Clinical Applied Value of the Early Slope Value of MR Contrast-Enhancement in Differentitating Benign Musculoskeletal Neoplasms from Malignant Ones
- VernacularTitle:早期动态MRI增强斜率值对肌肉骨骼系统良恶性肿瘤的鉴别诊断价值及临床研究
- Author:
Huili GUO
;
Min ZHANG
;
Jingliang CHENG
- Publication Type:Journal Article
- Keywords:
bone;
soft tissue;
neoplasm;
MR imaging;
dynamic contrast-enhancement
- From:
Journal of Practical Radiology
2000;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical applied value of the early slope value of MR contrast-enhancement in differentitating benign from malignant musculoskeletal neoplasms.Methods 48 patients with benign or malignant musculoskeletal masses(26 benign,22 malignant) confirmed by pathology underwent dynamic contrast-enhanced scanning.The largest slope of dynamic enhancement in early stage and SI-Time curve type were gained and the difference of them in benign and malignant musculoskeletal tumours were analysed.Spearman rank correlation analysis was used to determine the relation between slope and microvessel density of tumor tissues.Results There were 3 SI-Time curve types in all cases with typeⅠ(precipitous rise) in 22 cases,type Ⅱ(slow rise) in 21 cases and type Ⅲ(slight rise) in 5 cases.The average early slope value of enhancement was(4.23?2.68)% per second(range 0.96%~10.53%)in malignant tumors,and(1.44?0.99)% per second(range 0.36%~3.76%)in benign tumors.There was an apparent statistical significance between benign and malignant tumors(P