The expression of 4-1BB and GITR on CD4~+CD25~(high) T cells in peripheral blood of patients with multiple sclerosis
- VernacularTitle:多发性硬化患者外周血CD4~+CD25~(high) T细胞上4-1BB和GITR的表达
- Author:
Guangzhi LIU
;
Xuguang GAO
- Publication Type:Journal Article
- Keywords:
GITR;
4-1BB;
Multiple sclerosis;
Peripheral blood;
CD4~+CD25~+ regulatory T cell
- From:
Chinese Journal of Immunology
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).Conclusion:The decrease in 4-1BB expression,rather than the GITR expression,on CD4+CD25high T cells of MS patients suggests that 4-1BB may be involved in the lower immunoactivity of the cell population,while the GITR may play a minor or fine role in the immunoregulation of the cells.