Association of HLA-DRB1 alleles with vitiligo and psoriasis vulgaris in Chinese Han people of Jilin region
- VernacularTitle:HLA-DRB1等位基因与吉林地区汉族白癜风和寻常型银屑病相关性研究
- Author:
Xueying WANG
;
Rihua JIANG
;
Mingji ZHU
;
Xianghui CHEN
;
Zhen DONG
- Publication Type:Journal Article
- Keywords:
Vitiligo;
Psoriasis vulgaris;
HLA-DRB1 allele;
PCR-SSP
- From:
Chinese Journal of Immunology
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify the HLA-DRB alleles associated with vitiligo and psoriasis in Chinese Han people of Jilin region.Methods:HLA-DRB alleles of 82 vitiligo patients and 80 psoriasis vulgaris patients were detected by polymerase chain reaction sequence-specific primer(PCR-SSP),under the comparison with 86 healthy persons.Results:①The frequence of HLA-DRB1* 07 and HLA-DRB1*12 alleles increased obviously in vitiligo group compared with control group(P
