Iron Element and Parkinson’s Disease
- VernacularTitle:铁元素与帕金森病
- Author:
Chunyang DONG
;
Defu HE
;
Enqi WENG
- Publication Type:Journal Article
- Keywords:
Iron;
Iron metabolism;
Parkinson’s disease;
Neurotoxicity;
Lipid peroxidation
- From:
Journal of Environment and Health
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Iron is abnormally accumulated in the substantia nigra pars compacta (SNc) in Parkinson’s disease (PD) patients. The disorder of iron metabolism and the neurotoxicity induced by excessive iron are proved in PD patients, and these indicate that iron is closely correlative with PD. This article presented an overview of research advances of three aspects including the distribution and metabolism of iron in the brain, the neurotoxicity of iron, and the relationship between the disorder of iron metabolism in central nervous system and PD.
