The effects and mechanism of Alprostadil combined with Shuxuetong treatment on diabetic peripheral neuropathy
- VernacularTitle:前列地尔联合疏血通治疗糖尿病周围神经病变的疗效及其机制
- Author:
Qingbin ZHAO
;
Chaofeng SUN
;
Aiqun MA
;
Changcong CUI
- Publication Type:Journal Article
- Keywords:
Alprostadil;
Shuxuetong;
diabetic peripheral neuropathy;
oxidative stress
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effects of Alprostadil combined with Shuxuetong treatment on patients with diabetic peripheral neuropathy,and its influence on malondialdehyde(MDA),superoxide dismutase(SOD) and total antioxidative capability(TAOC).Methods Totally 160 patients with DPN were divided into two groups: treatment group(100 cases) and control group(60 cases).The levels of blood SOD activity,serum MDA and serum TAOC were determined before and after treatment.Results The symptoms in both groups were significantly improved,but the total effective rate in treatment group was significantly better than that in control group(80.0% vs.41.7%,P
