Study on methylation of sodium iodide symporter gene promoter in papillary thyroid carcinoma
- VernacularTitle:甲状腺乳头状癌组织中钠碘转运体基因启动子甲基化的研究
- Author:
Jiandong TANG
- Publication Type:Journal Article
- Keywords:
Papillary thyroid carcinoma;
Gene;
sodium iodide symporter;
DNA methylation;
Methylation-specific PCR
- From:
Chinese Journal of Endocrinology and Metabolism
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The methylation-specific PCR technique was applied to detect the promoter methylation of sodium iodide symporter(NIS)gene in 34 cases of papillary thyroid carcinoma(PTC)and adjacent thyroid tissure (ATF).The results showed that the methylation of NIS promoter in PTC was significantly higher than that in ATT (P
