Relationshinp between the expression of CXCR4 and VEGF-C with lymph node metastasis in human rectal cancer
- VernacularTitle:人直肠癌组织中CXCR4和VEGF-C表达及其与淋巴结转移之间关系的研究
- Author:
Sifeng TANG
;
Jianliang ZHANG
;
Qinye FU
;
Jingyuan WANG
- Publication Type:Journal Article
- Keywords:
Chemokine receptor CXCR4? Vascular endothelial growth factor C? Rectal carcinoma?Lymphatic metastasis
- From:
Chinese Journal of Current Advances in General Surgery
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the relationship between the expressions of chemokine receptor CXCR4 and vascular endothelial growth factor C (VEGF-C ) with lymph node metastasis in human rectal cancer. Methods: Immuohistochemical staining was used to detect the expressions of CXCR4 and VEGF-C in 73 samples of human rectal cancer. The relationship between CXCR4 and VEGF-C in 73 samples of human rectal cancer. The relationship between CXCR4 and VEGF-C expressions was analyzed. Results: The positive rate of CXCR4 expression with lymph node metastasis was higher than that without lymph node metastasis (60.1% vs 23.3%,P