Tenascin(TN) expressions and its effect in salivary gland tumor
- VernacularTitle:肌腱抗原在涎腺恶性肿瘤中的表达及意义
- Author:
Zhong BIN
;
Ma KAI
;
Qian JIN
- Publication Type:Journal Article
- Keywords:
Tenascin;
Immunohistochemistry;
Salivary gland tumor
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To detect tenascin(TN) expressions and its effect in salivary gland tumor. Methods:The expressions of TN was examined in 8 chronic inflammations of salivary glands, 50 benign adenomas and 57 malign adenomas by Envision immunohistochemical technique. Results:Expression level of TN in the malign adenomas was higher than that in benign adenoma and chronic sialadenitis; higher in low differentiation than that in high differentiation and higher in lymphatic metastasis groups than that without lymphatic metastasis groups. No obviously difference was found between soakage inside the blood vessel and nerves and without soakage. Conclusion: TN might regulate cell attachment of epithelial cells in adenomas, and involve in adenomas' histogenesis and development.
