The affection of Ku70 mRNA expression to tumor and drug resistance in human lung cancer
- VernacularTitle:Ku70 mRNA表达与人非小细胞肺癌化学治疗耐受性关系的研究
- Author:
Jie ZHANG
;
Yarong LI
;
Zhenzhong SU
;
Xiaowen ZHENG
;
Yunxia ZHANG
;
Yue ZHI
- Publication Type:Journal Article
- Keywords:
Lung cancer;
Ku70 mRNA expression;
Chemotherapy
- From:
Chinese Journal of Immunology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the relationship between Ku70 mRNA expression in non-neoplasm,in normal appearing pulmonary tissues,and in lung cancer tissue of pre-or post-chemotherapy and drug resistance.Methods:Ku70 mRNA in the lung tissues was measured by reverse transcription polymerase chain reaction (RT-PCR).The samples were extracted form 26 non-neoplasm, normal appearing pulmonary tissues and 56 lung cancer tissues.Results:Non-neoplasm, normal appearing pulmonary tissue group expressed Ku70 mRNA lower than lung cancer tissue group(P
