Effects of Selenium,Germanium Combination on Calcium,Magnesium,Zincum Level in Serum, Liver,Kidney of Rats Exposed to Fluoride
- VernacularTitle:硒和锗对氟染毒大鼠血清和组织中钙和镁及锌的影响
- Author:
Xiujuan YUAN
;
Limin NIU
;
Liping YU
- Publication Type:Journal Article
- Keywords:
Fluoride;
Selenium;
Germanium;
Antagonism
- From:
Journal of Environment and Health
2007;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the combined effects of selenium (Se), germanium (Ge) on the level of Ca, Mg, Zn in the tissues of rats exposed to fluoride(F). Methods SD rats were divided into 5 groups and respectively treated with distilled water(control), 100 mg NaF/L(through drinking water), based on the fluoride treatment, Se, Ge were respectively given by gavage at the doses of 0.1 mg Na2SeO3/(kg?d), 10 mg Ge-132/(kg?d) and 0.1 mg Na2SeO3/(kg?d) plus 10 mg Ge-132/(kg?d) for 90 days. The body weight, activity, and general state were observed. The content of Ca,Mg,Zn in the serum,liver and kidneys were determined by flame atomization method. The content of F was detected by ion chromatography. Results The body weight in F+Se, F+Ge and F+Se+Ge groups were higher than that in F group and lower than that in the control group. The content of F in the liver, kidney in F+Se, F+Ge groups were higher than that in F+Se+Ge group(P
