Determination of Dibutyl Phthalate and Bis(2-ethylhexyl) Phthalate in Cosmetics by Gas Chromatography-Mass Spectrometry
- VernacularTitle:化妆品中邻苯二甲酸酯的气相色谱-质谱测定法
- Author:
Xiangping LIU
;
Wei HUANG
;
Chunye LI
- Publication Type:Journal Article
- Keywords:
Cosmetics;
Dibutyl phthalate;
Bis(2-ethylhexyl) phthalate;
Gas chromatography-mass spectrometry
- From:
Journal of Environment and Health
2007;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop a method for the determination of DBP and DEHP in cosmetics by GC-MS. Methods The samples was extracted by methanol or acetic ether, DBP and DEHP were separated by GC and determined by MS. Results The linear range, regression equation of calibration curve and correlation coefficient were 0.5-100.0 ?g/ml, y=2?106 x-2?106, 0.999 6 for DBP respectively and 5.5-110.0 ?g/ml, y=988 223 x-7?106, 0.995 9 for DEHP respectively. Based on threefold ratio of signal and noise, as the sample was 1.0 and 0.2 g respectively, the volume was 10.0 ml, the detection limits were 1.0 and 5.0 mg/kg respectively for both DBP and DEHP. The recovery rates were 90.8%-119.0% for DBP and 90.4%-115.3% for DEHP. Relative standard deviations were 4.8%-9.8% for DBP and 6.0%-8.6% for DEHP. Conclusion This method is sensitive, accurate and high reproducible, and was applicable to the determination of DBP and DEHP in the cosmetics.
