Determination of Sudan Ⅰ-Ⅳ and Dye Para Red in Lipstick by HPLC
- VernacularTitle:唇用化妆品中苏丹Ⅰ~Ⅳ及对位红的高效液相色谱测定法
- Author:
Baokun GE
;
Qiyong CHEN
;
Kongxiang ZHAO
- Publication Type:Journal Article
- Keywords:
Cosmetics;
Sudan Ⅰ-Ⅳ;
Dye para red;
Chromatography, liquid
- From:
Journal of Environment and Health
2007;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish an HPLC method to determine sudan Ⅰ-Ⅳ and dye para red in the lipstick. Methods The samples were extracted with the acetonitrile, after centrifuge and filter, the extracted solution was tested by HPLC-UV and the external standard method was employed to do the quantitative analysis. Results As the concentrations was 1.0 mg/kg, the mean recovery rates were 93%-97%, the RSD was less than 4.6%, the detection limit was 0.05 mg/kg and the linear range was 0.2-5.0 mg/kg(the correlative coefficient ranged 0.998 5-0.999 8). Conclusion This method is simple, accurate, rapid and applicable to the determination of sudan I-IV and dye para red in the lipsticks.