Preliminary investigation on Immune-Inflammation in Type 2 Diabetes
- VernacularTitle:2型糖尿病免疫炎症的初步探讨
- Author:
Xiaoyan WU
;
Xulei TANG
;
Lin GAO
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus;
T helper cells;
Hs-CRP;
Immune inflammation;
Flow cytometry
- From:
Chinese Journal of Immunology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical significance of Th1/Th2 balance of peripheral blood Th cells and of serum high-sensitivity C-Reactive Protein(hs-CRP) in type 2 diabetic patients.Methods:Th1/Th2 cells were determined by using the tri-colored fluorescence labeled flow cytometry serum hs-CRP concentrations were determined by ELISA in type 2 diabetic patients (n=60) and the controls (n=25).Results:(1)Th1 cells and Th1/Th2 ratios were significantly reduced in type 2 diabetic patients than the controls (P 0.05 ). Th1 cells negatively correlated with HbA1c (r=-0.688 P
