The effect of estrogen and recombine human growth hormone on residual ridge reduction in osteoporotic rats
- VernacularTitle:重组人生长激素、雌激素联合应用对去势大鼠剩余牙槽骨吸收的影响
- Author:
Chengfang TANG
;
Xiaohong LI
;
Sanping GUO
;
Zhuo XIAO
;
Yajun HU
- Publication Type:Journal Article
- Keywords:
osteoporosis;
recombine human growth hormone;
estrone;
resorption of residual ridge;
tartrate-resistant acid phosphatase;
bone histomorphometry;
rat
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of estrogen,recombine human growth hormone and their combinations on residual ridge reduction in osteoporotic rats.Methods Animal models were established by ovariectomy and exodontia on left partial maxillary,then were devided into osteoporosis group and treatment groups;treatment groups were given estrogen and recombine human growth hormone medicial alone and their recombinations.After treatment for 4 and 8 weeks with drugs,the effects of estrogen and recombine human growth hormone on the serum tartrate-resistant acid phosphatase level and bone histomorphometry changes in maxillary were observed in each group. Results ① The serum tartrate-resistant acid phosphatase level was obvionsly lower in ERT group and Er-HGH group than in OP group(P