Advances in the study of carcinoma-associated fibroblasts
- VernacularTitle:肿瘤相关纤维母细胞的研究进展
- Author:
Minjie JU
;
Shuangjian QIU
;
Zhaoyou TANG
- Publication Type:Journal Article
- Keywords:
tumor;
stroma;
carcinoma-associated fibroblasts
- From:
China Oncology
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
The biological characteristic of carcinomas is determined both by the stromal microenvironment and the oncogene or anti-oncogene.The tumor stroma is also known as the reactive stroma which is composed of base member,immunocell,capillary,fibroblasts and ECM.Fibroblasts are the majority of tumor stromal cells.The relationship between fibroblasts and the initiation,progression of carcinoma has being in the spot light.In this review,we summarized the advance in the study of carcinoma-associated fibroblasts.