Combined Effect of Arsenite and Cigarette Smoke Solution on NF-?B in Lymphocytes of Rats
- VernacularTitle:砷和香烟烟气溶液联合作用对大鼠淋巴细胞核因子?B的影响
- Author:
Yi WANG
;
Xin LI
;
Bing LI
- Publication Type:Journal Article
- Keywords:
Arsenism;
Arsenite;
Cigarette smoke solution;
Nuclear factor-?B
- From:
Journal of Environment and Health
2007;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of sodium arsenite combined with cigarette smoke solution on NF-?B in rat lymphocytes. Methods Rat lymphocytes were divided into 4 groups: the arsenite treatment group, the CSS treatment group, the arsenite and CSS treatment group, and the control group. Electrophoretic mobility shift assays was used to detect levels of NF-?B DNA binding. Western blot was used to detect protein expression of I?B?. Results Levels of NF-?B DNA binding in the CSS treatment group and the arsenite treatment group were significantly increased (P
