Effect of Cold Stress on Artery Pressure and Serum Cytokines of Rabbits
- VernacularTitle:冷应激家兔血压与血清细胞因子的变化及其相互关系
- Author:
Dongmei JIANG
;
Shize LI
;
Huanmin YANG
- Publication Type:Journal Article
- Keywords:
Cold stress;
Rabbit;
Blood pressure;
Cytokines
- From:
Journal of Environment and Health
2007;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To know the effect of cold stress on the artery pressure and the concentration of IL-2, IL-10, IFN-?, TNF-? in the serum of the rabbits. Methods The local white rabbits of China (clean grade) were anesthetized. The mAP (mean artery pressure), mSP (mean systolic pressure), mDP (mean diastolic pressure) and the concentration of IL-2, IL-10, IFN-?, TNF-? were determined at 0 h, 0.25 h, 0.50 h, 0.75 h, 1.00 h, 1.50 h, 2.00 h, 3.00 h, 4.00 h and 6.00 h after cold stress. Results The mAP,mSP and mDP changed undulant with the delay of cold stress,but the whole tendency was descendent. The mAP,mSP and mDP went up to the peak at 1 h,however lower than control. The concentration of IL-2 increased then decreased with the delay of cold stress,the concentration of IL-10 went down then up and the concentration of TNF-?,IFN-? went down gradually. There was a strong correlation between IFN-? and TNF-? (r=0.983 0,P
