Expression of co-stimulatory molecules in idiopathic thrombocytopenic purpura
- VernacularTitle:特发性血小板减少性紫癜患者协同刺激分子的表达
- Author:
Jianling PAN
;
Xiuru GUAN
;
Xuehua MA
;
Xin HE
- Publication Type:Journal Article
- Keywords:
Idiopathic thrombocytopenic purpura;
Co-stimulatory molecules;
Lymphocyte
- From:
Chinese Journal of Immunology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The research was performed to understand the expression of CD80,CD86 and its ligand CD28 on peripheral lymphocytes in patients suffered from idiopathic thrombocytopenic purpura(ITP).Methods:The expression of co-stimulatory molecules(CD80,CD86 and its ligand CD28)on peripheral lymphocytes from 34 ITP patient samples and 34 normal samples was detected by immunofluorescence and flow cytometry.Results:The expression of CD80 and CD86 on peripheral lymphocytes from ITP patients(4.21?2.27%,7.19?5.16%) was higher than that of the normal samples as control(2.34?0.87%,4.08?1.96%,p
